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Prevalence of Cerebral Microbleeds in Thai Patients with Ischemic Stroke

Artit Potigumjon1, Arvemas Watcharakorn2, Pornpatr A Dharmasaroja3

  • 1Department of Internal Medicine, Faculty of Medicine, Thammasat University, Thailand.

Journal of Neurosciences in Rural Practice
|May 9, 2017
PubMed
Abstract

Insights

Cerebral microbleeds (CMBs) affect 20% of Thai ischemic stroke patients. Hypertension and severe white matter lesions are associated with CMBs, offering insights into stroke risk factors.

Area of Science:

  • Neurology
  • Radiology
  • Stroke Research

Background:

  • Cerebral microbleeds (CMBs) are increasingly detected via MRI.
  • Ethnicity may influence CMB prevalence, with higher rates observed in Asian populations.
  • Understanding CMB prevalence in specific ethnic groups, like Thai patients with ischemic stroke, is crucial.

Purpose of the Study:

  • To determine the prevalence of cerebral microbleeds (CMBs) in Thai patients diagnosed with ischemic stroke.
  • To identify factors associated with the presence of CMBs in this patient cohort.

Main Methods:

  • A study cohort of 200 patients with acute ischemic stroke was analyzed.
  • Magnetic resonance imaging (MRI) using T2*-weighted gradient-recalled echo was employed to detect CMBs.
  • Baseline characteristics, stroke subtypes, and white matter lesion severity were compared between patients with and without CMBs.

Main Results:

  • The prevalence of CMBs was 20% (39 out of 200 patients).
  • Hypertension was significantly associated with CMBs (OR 3.05, P=0.037).
  • Moderate-to-severe white matter lesions (Fazekas 2-3) showed a strong association with CMBs (OR 7.61, P<0.001).

Conclusions:

  • Cerebral microbleeds (CMBs) were present in 20% of Thai ischemic stroke patients.
  • This prevalence is lower than in Japanese studies but comparable to Chinese findings.
  • CMBs in ischemic stroke patients are linked to hypertension and the severity of white matter lesions.
Keywords:
AsianThaicerebral microbleedischemic stroke

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