Related Experiment Video
Updated: Mar 2, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
Published on: June 12, 2021
Life-Threatening Hemopericardium Associated with Rivaroxaban
Sijan Basnet1, Niranjan Tachamo1, Biswaraj Tharu2
1Department of Medicine, Reading Health System, West Reading, PA 19611, USA.
Rivaroxaban, a novel oral anticoagulant, can cause rare side effects. A patient developed spontaneous hemopericardium, a serious condition, highlighting the need for clinical awareness with increased anticoagulant use.
Area of Science:
- Cardiology
- Pharmacology
- Internal Medicine
Background:
- Rivaroxaban is a widely used novel oral anticoagulant for venous thromboembolism.
- Its clinical use has increased, leading to a broader understanding of its side effect profile.
- Adverse events associated with anticoagulants require continuous monitoring and reporting.
Observation:
- A 56-year-old female presented with acute shortness of breath and chest pain.
- Symptoms appeared 12 weeks after initiating rivaroxaban for deep vein thrombosis.
- Initial presentation mimicked other cardiopulmonary conditions.
Findings:
- The patient was diagnosed with spontaneous hemopericardium, a rare complication.
- The condition necessitated urgent pericardial fluid drainage.
- No other cause for hemopericardium was identified.
Implications:
- This case underscores rare but serious adverse effects of novel oral anticoagulants.
- Clinicians must consider spontaneous hemopericardium in patients on rivaroxaban presenting with chest pain and dyspnea.
- Increased vigilance is crucial for early diagnosis and management of anticoagulant-related complications.
Related Concept Videos
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Pulmonary Embolism I: Introduction
Venous Thrombosis III: Interprofessional Care
Anticoagulant Drugs: Low-Molecular-Weight Heparins
Venous Thrombosis IV: Nursing Management
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.

