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Updated: Mar 2, 2026

Isolation and Flow Cytometric Analysis of Human Endocervical Gamma Delta T Cells
Published on: February 6, 2017
Prevalence and Transmission of Beta and Gamma Human Papillomavirus in Heterosexual Couples
Anna-Barbara Moscicki1, Yifei Ma2, Tarik Gheit3
1Department of Pediatrics, Division of Adolescent Medicine, University of California, Los Angeles.
Background:
Beta (β) and gamma (γ) human papillomavirus (HPV) are commonly found on the skin. Few of the β types are associated with nonmelanoma skin cancer. Little is known about transmission patterns of these HPV, specifically in the anogenital (AG) areas. The primary objective of this study was to examine the AG concordance and transmission of β and γHPV types between heterosexual couples.
Methods:
Archival samples from a previously published study examining concordance of alpha HPV types between couples were tested for β and γHPV. Hand, mouth, and genital samples were obtained 5 times over a 6-week period.
Results:
Of the 21 couples examined, β and γHPV were detected in AG sites in 67% and 30% of men, respectively, and 41% and 25% of women. Positive concordance for β and γHPV was 27% and 20%, respectively, which was greater than the observed concordance between noncouples (10% for βHPV and 4% for γHPV). Transmission rate of βHPV between AG areas was 15.9 (95% confidence interval [CI], 3.3-46.5) per 100 person months for men-to-women at risk and for γHPV was 6.6 (95% CI, .2-36.7). Risks for women-to-men were similar.
Conclusions:
Beta and γHPV are common in the AG area, and data suggest that they can be sexually transmitted.
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