Related Experiment Video

Updated: Mar 2, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.7K

An Uncommon Site of Streptococcus pneumoniae Colonization Leading to Recurrent Pneumococcal Disease

Parham Sendi1,2, Eva Maria Moser Schaub3, Konstantinos Nirgianakis4

  • 1Departments of Infectious Diseases.

Open Forum Infectious Diseases
|May 9, 2017
PubMed

Insights

This case study shows a woman who experienced recurrent pneumococcal peritonitis, likely due to an intrauterine device. Vaccination with a pneumococcal conjugate vaccine led to increased antibody levels and prevented further infections.

Area of Science:

  • Infectious Diseases
  • Immunology
  • Gynecology

Background:

  • Recurrent pneumococcal peritonitis is a rare but serious condition.
  • Intrauterine devices (IUDs) have been associated with an increased risk of pelvic inflammatory disease.
  • Vaginal colonization with Streptococcus pneumoniae can be a source of infection.

Purpose of the Study:

  • To describe a case of relapsing pneumococcal peritonitis.
  • To investigate the potential role of an intrauterine contraceptive device in recurrent infection.
  • To evaluate the efficacy of pneumococcal conjugate vaccine in preventing recurrence.

Main Methods:

  • Case report.
  • Clinical observation.
  • Serological testing for pneumococcal antibodies before and after vaccination.

Main Results:

  • The patient experienced recurrent episodes of pneumococcal peritonitis.
  • Vaginal colonization with Streptococcus pneumoniae was identified as the likely source.
  • Immunization with a pneumococcal conjugate vaccine resulted in elevated antibody titers.
  • The patient remained free of infection at a 2-year follow-up.

Conclusions:

  • An intrauterine contraceptive device can serve as a nidus for recurrent pneumococcal peritonitis in colonized women.
  • Pneumococcal conjugate vaccination may be an effective strategy for preventing recurrent infections in susceptible individuals.
  • This case highlights the importance of considering IUDs in the differential diagnosis of recurrent peritonitis.
Keywords:
Streptococcus pneumoniaeperitonitistertiary peritonitis.

More Related Videos

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling08:25

Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling

Published on: April 7, 2015

9.6K
Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae09:12

Characterization of Inflammatory Responses During Intranasal Colonization with Streptococcus pneumoniae

Published on: January 17, 2014

13.2K

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
1.1K
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
3.6K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
1.0K
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
3.7K
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture01:26

Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture

Sputum studies are a critical part of diagnosing and treating numerous respiratory conditions. These studies involve obtaining sputum samples for analysis to identify pathogenic organisms and assess the presence of abnormal cells indicative of malignant conditions. This lesson will delve into three fundamental sputum studies: Gram Stain, Cytology, and Acid-fast Smear and Culture.
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
819
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.2K