Variation in plasma cytokine concentration during a training season in elite kayakers
Grasiely F Borges1,2, Luis Rama1, Humberto M Carvalho3
1Center for Sport and Physical Activity, Faculty of Sport Sciences and Physical Education, University of Coimbra, Coimbra, Portugal.
Background:
The purpose of this study was to investigate the differences in cytokines levels in the peripheral blood of kayakers at different moments of training.
Methods:
The sample comprised 12 elite kayakers preparing for the Beijing Olympic Games. Blood samples were collected at different time points of the training season: baseline (t0-November) after 6 weeks of off-training and before the start of the training season; t1 (January) at week 11 after a period of high-volume training; t2 (April) at week 26 at the end of a period of high intensity training sessions; t3 (June) at week 31 after a competitive period.
Results:
Decreases in cytokine levels were found for IL-1β and IL-18 at t1. IL-1 then increased throughout the remaining training season while IL-18 leveled off towards the end of the season. IL-1ra showed an exponential increase at t2 before leveling-off in the last period of training. No significant changes were found for IL-6, IFN-γ and TNF-α. No differences were observed in the magnitude and pattern of cytokines changes across the training season between the elite female and male kayakers.
Conclusions:
Increases in training volume were able to induce decreases in pro-inflammatory plasma cytokine coinciding with the reported increase in upper respiratory tract infections in the kayakers.
