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Gene Evolution - Fast or Slow?

Gene Evolution - Fast or Slow?

The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...

Gene Evolution - Fast or Slow?

Gene Evolution - Fast or Slow?

Evolutionary Relationships through Genome Comparisons

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...

Speciation Rates

Speciation Rates

Phylogenetic Trees

Phylogenetic Trees

Phylogenetic trees come in many forms. It matters in which sequence the organisms are arranged from the bottom to the top of the tree, but the branches can rotate at their nodes without altering the information. The lines connecting individual nodes can be straight, angled, or even curved.

Phylogeny

Phylogeny

Phylogeny is concerned with the evolutionary diversification of organisms or groups of organisms. A group of organisms with a name is called a taxon (singular). Taxa (plural) can span different levels of the evolutionary hierarchy. For instance, the group containing all birds is a taxon (comprising the class Aves), and the group of all species of daisies (the genus Bellis) is a taxon. Phylogenies can likewise include just one genus (i.e., depict species relationships) or span an entire kingdom.

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Updated: Mar 2, 2026

A Practical Guide to Phylogenetics for Nonexperts

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

ModelFinder: fast model selection for accurate phylogenetic estimates.

Subha Kalyaanamoorthy^1,2, Bui Quang Minh³, Thomas K F Wong^1,4

¹Land &Water, CSIRO, Canberra, Australian Capital Territory, Australia.

|May 9, 2017

Summary

This summary is machine-generated.

ModelFinder accurately improves phylogenetic estimates by selecting better evolutionary models. This method incorporates new rate heterogeneity models and searches both model and tree spaces simultaneously.

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Published on: February 5, 2014

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Published on: August 14, 2018

A Concoction Pipeline for Generating Molecular Operational Taxonomic Units (MOTUs) Among Riparian and Aquatic Beetles

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Published on: July 11, 2025

Area of Science:

Genomics
Molecular Phylogenetics
Computational Biology

Background:

Model-based molecular phylogenetics is crucial for genomic data comparison.
Accurate model selection is essential for reliable phylogenetic analyses.

Purpose of the Study:

To introduce ModelFinder, a novel and efficient method for selecting evolutionary models.
To enhance the accuracy of phylogenetic estimates through improved model selection.

Main Methods:

Developed ModelFinder, a fast model-selection tool.
Incorporated a previously unconsidered model of rate heterogeneity across sites.
Enabled concurrent searches of both model and tree spaces.

Main Results:

ModelFinder significantly improves the accuracy of phylogenetic estimates.
The new method offers a faster approach to model selection.

Conclusions:

ModelFinder represents a significant advancement in model selection for molecular phylogenetics.
The concurrent search strategy and novel heterogeneity model enhance phylogenetic inference accuracy.