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Core-Shell-structured Dendritic Mesoporous Silica Nanoparticles for Combined Photodynamic Therapy and Antibody
Prasanna Lakshmi Abbaraju1, Yannan Yang1, Meihua Yu1
1Australian Institute of Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD-, 4072, Australia.
Chemistry, an Asian Journal
|May 9, 2017
Abstract:
Multifunctional core-shell-structured dendritic mesoporous silica nanoparticles with a fullerene-doped silica core, a dendritic silica shell and large pores have been prepared. The combination of photodynamic therapy and antibody therapeutics significantly inhibits the cancer cell growth by effectively reducing the level of anti-apoptotic proteins.
