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Immunotherapy of mold allergy: A review

A Bozek1, K Pyrkosz1

  • 1a Clinical Department of Internal Disease, Dermatology and Allergology , Medical University of Silesia , Katowice , Poland.

Human Vaccines & Immunotherapeutics
|May 9, 2017
PubMed

Insights

Mold allergies affect the respiratory system, causing rhinitis and asthma. Allergen specific immunotherapy (AIT) for molds is common but currently limited to Alternaria, with this review discussing its benefits and challenges.

Area of Science:

  • Allergy and Immunology
  • Environmental Health

Background:

  • Mold allergies are prevalent, primarily impacting the respiratory system and manifesting as allergic rhinitis and bronchial asthma.
  • Molds represent a diverse group of allergens capable of triggering various allergic responses.

Purpose of the Study:

  • To review the benefits and challenges of allergen specific immunotherapy (AIT) for mold allergies.
  • To discuss the current limitations of mold-specific AIT, which is primarily available for Alternaria.

Main Methods:

  • Literature review of existing studies on mold allergies and AIT.
  • Inclusion of expert experience and insights regarding AIT for molds.

Main Results:

  • Allergen specific immunotherapy (AIT) for molds is widely practiced.
  • Current AIT for molds is predominantly limited to Alternaria species.
  • The review highlights both the advantages and disadvantages associated with mold AIT.

Conclusions:

  • While AIT is a common treatment for mold allergies, its application is currently restricted.
  • Further research and development are needed to expand AIT options for a broader range of mold allergens.
  • Understanding the benefits and problems of current mold AIT is crucial for optimizing patient care.
Keywords:
AlternariaCladosporiumIgEimmunotherapymold

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