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Incidental Prostate-Specific Membrane Antigen Uptake in a Peripheral Nerve Sheath Tumor
Shankar Vamadevan1, Ken Le, Lily Shen
1From the *Department of Nuclear Medicine and PET Nepean Hospital, Penrith; and †Nepean Medical School, University of Sydney, Sydney, New South Wales, Australia.
Abstract:
A 66-year-old man with recently diagnosed prostate cancer (Gleason score 9) was referred for Ga-prostate-specific membrane antigen (PSMA) PET/CT with prostate-specific antigen level of 7.5 μg/L. PET/CT demonstrated increased PSMA uptake (SUVmax 4.7) in a soft tissue density in the left adductor compartment. MRI and cytopathology of the biopsied soft tissue density was compatible with a peripheral nerve sheath tumor. This case illustrates that PSMA uptake can occur in a peripheral nerve sheath tumor and should be taken into consideration as a benign cause of PSMA uptake.
