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Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy.
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Related Experiment Video

Updated: Mar 2, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
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Pathview Web: user friendly pathway visualization and data integration.

Weijun Luo1,2, Gaurav Pant1,3, Yeshvant K Bhavnasi1,3

  • 1Department of Bioinformatics and Genomics, UNC Charlotte, Charlotte, NC 28223, USA.

Nucleic Acids Research
|May 9, 2017
PubMed
Summary
This summary is machine-generated.

Pathview Web offers an accessible platform for pathway analysis, integrating and visualizing omics data. This tool empowers scientists with user-friendly features for biological data interpretation.

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Area of Science:

  • Bioinformatics
  • Computational Biology
  • Genomics

Background:

  • Pathway analysis is crucial for interpreting omics data.
  • Integrating and visualizing diverse biological datasets onto pathways remains a challenge.
  • Existing tools may require specialized computational skills.

Purpose of the Study:

  • To develop an accessible web server for pathway visualization and data integration.
  • To expand the capabilities of the Pathview R package for broader scientific use.
  • To provide a comprehensive workflow for analyzing multiple omics datasets.

Main Methods:

  • Development of the Pathview Web server with a graphical user interface.
  • Integration of core Pathview functionalities with enhanced features.
  • Implementation of a RESTful API for programmatic access.

Main Results:

  • Pathview Web provides an intuitive platform for pathway analysis.
  • The server supports integration of various omics data types.
  • It offers advanced features beyond the original R package.

Conclusions:

  • Pathview Web democratizes pathway analysis for researchers lacking specialized skills.
  • The platform facilitates integrated analysis of multiple omics datasets.
  • It serves as a valuable resource for biological data interpretation and discovery.