Genetic and Functional Characterization of blaCTX-M-199, a Novel Tazobactam and Sulbactam Resistance-Encoding Gene
Jiachang Cai1, Qipeng Cheng2,3, Yingbo Shen4
1Clinical Microbiology Laboratory, The Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Antimicrobial Agents and Chemotherapy
|May 10, 2017
Abstract:
We report the genetic and functional characterization of a novel CTX-M-199 β-lactamase, which was encoded by a blaCTX-M-64 variant gene found in a conjugative mcr-1-bearing IncI2 plasmid and exhibited resistance to β-lactamase inhibitors, tazobactam, and sulbactam.
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