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The binding characteristics of the cytochrome c iron
1Lady Davis Chair of Biochemistry, Sackler Institute of Molecular Medicine, Sackler Medical School, Tel Aviv University, Israel.
The Biochemical Journal
|October 1, 1988
Abstract:
A comparison of the binding properties of myoglobin and cytochrome c shows that the latter, in the reduced state, has an unusually large affinity for ligands, including thioethers. This explains the outstanding stability of the methionine-iron bond of ferrous cytochrome c, and results from the intrinsic ability of the cytochrome c iron to delocalize its electrons into orbitals of the sixth axial ligand.