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Related Experiment Video

Updated: Mar 2, 2026

Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction
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Decrease of Horizontal Canal Vestibulo-Oculomotor Reflex Gain in the Elderly with Dysequilibrium without Lifetime

Roberto Teggi1, Matteo Trimarchi, Omar Gatti

  • 1ENT Department, San Raffaele Scientific Hospital, Milan, Italy.

ORL; Journal for Oto-Rhino-Laryngology and Its Related Specialties
|May 10, 2017
PubMed
Summary
This summary is machine-generated.

The horizontal canal function, measured by vestibulo-ocular reflex (VOR) gain, decreases with age in older adults. This decline in VOR gain is linked to an increased risk of falls in the elderly.

Keywords:
DysequilibriumElderlyPresbystasisVestibular functionVestibulo-ocular reflexVideo head impulse test

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Area of Science:

  • Gerontology
  • Neuroscience
  • Ophthalmology

Background:

  • Unsteadiness is common in the elderly, predicting falls and distress.
  • Vestibular system aging is increasingly recognized as a factor in elderly unsteadiness.
  • Horizontal canal function in older adults requires further investigation.

Purpose of the Study:

  • To assess the function of the horizontal semicircular canal in the elderly population.
  • To investigate the relationship between horizontal vestibulo-ocular reflex (VOR) gain and age-related factors.
  • To determine if VOR gain is associated with clinical conditions and fall history.

Main Methods:

  • Evaluated horizontal VOR gain using the video head impulse test.
  • Recruited 58 subjects over 70 years old with no history of vertigo.
  • Correlated VOR gain with hypertension, diabetes, cerebrovascular disorders, and fall history.

Main Results:

  • Mean VOR gain was 0.86 ± 0.12.
  • Subjects aged 70-80 had higher VOR gain (0.90 ± 0.1) than those >80 (0.81 ± 0.13; p=0.025).
  • Previous cerebrovascular disorders predicted decreased VOR gain (p=0.0003); age, sex, and VOR gain predicted falls (p<0.0001).

Conclusions:

  • Data suggest a decrease in VOR gain with aging in the elderly.
  • Reduced horizontal canal function may contribute to fall risk in older adults.
  • Vestibular assessment is crucial for understanding and mitigating fall risk in the elderly.