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[Severe chronic Epstein-Barr virus infection with natural killer cell defect]
K Hartung1, S Le Blanc, A Franz
1Abteilung Immunologie und Transfusionsmedizin, Medizinischen Hochschule Hannover.
Deutsche Medizinische Wochenschrift (1946)
|December 16, 1988
Abstract:
Chronic Epstein-Barr virus infection was confirmed serologically in a 27-year-old man with pneumonia, splenomegaly, pancytopenia, arthritis, neuropathy and psychological changes. Immunological tests revealed a defect in the cytotoxic activity of the natural killer cells. Treatment with high doses of acyclovir intravenously and of antimycotic drugs dramatically and lastingly improved the patient's condition.