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Somatic symptoms are sensitive in predicting interstitial cystitis/bladder pain syndrome
I-Chun Chen1, MingHuei Lee2,3, Shang-Liang Wu4
11 Department of Psychiatry, Taichung Veterans General Hospital, Taiwan.
International Journal of Psychiatry in Medicine
|May 11, 2017
Summary
Patients with somatic symptoms have a significantly increased risk of developing interstitial cystitis/bladder pain syndrome. This finding suggests potential biological links between somatic symptoms and this condition.
Area of Science:
- Medical research
- Clinical epidemiology
- Urology
Background:
- Somatic symptoms involve physical complaints with disproportionate thoughts, feelings, and behaviors.
- Several diagnoses are characterized by somatic symptoms.
- Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic condition affecting the bladder.
Purpose of the Study:
- To investigate the risk of developing interstitial cystitis/bladder pain syndrome (IC/BPS) in patients with somatic symptoms.
- To test the hypothesis that somatic symptoms increase the risk of IC/BPS.
Main Methods:
- A longitudinal study using nationwide health insurance data from 2002-2013.
- Comparison of a somatic symptoms cohort (n=34,393) with a non-somatic symptoms cohort (n=637,999).
- Propensity score matching based on sex, age, and 17 comorbidities to stratify cohorts into three subgroups.
Main Results:
- Significantly different incidence densities of IC/BPS between cohorts across all three subgroups (RR 1.52-2.14).
- Increased adjusted hazard ratios for IC/BPS in female-dominant and older age subgroups (aHR 1.47-1.72).
Conclusions:
- Somatic symptoms are associated with a subsequent increased risk of interstitial cystitis/bladder pain syndrome.
- Potential biological pathways may link somatic symptoms to IC/BPS risk, similar to psychosocial factors.
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