Related Experiment Video
Updated: Mar 2, 2026
Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Quantification of Left Ventricle Function in Stress Echocardiography Using Endocardial Area Centroid Trajectory
Mohammad Jalali1, Hamid Behnam1, Maryam Shojaeifard2
1Department of Biomedical Engineering, Iran University of Science and Technology, Tehran, Iran.
Insights
New stress echocardiography methods reveal ischemic hearts struggle to increase activity during peak stress. This parameter quantifies left ventricular (LV) function by analyzing endocardial border variations, aiding in diagnosing cardiac dysfunction.
Area of Science:
- Cardiology
- Medical Imaging
- Echocardiography
Background:
- Coronary artery occlusion impairs cardiac function, leading to left ventricular (LV) wall motion abnormalities.
- Stress echocardiography enhances the detection of these abnormalities by exaggerating wall motion dysfunction under induced cardiac stress.
Purpose of the Study:
- To introduce and validate a novel parameter for measuring left ventricular (LV) function.
- To assess the utility of this parameter in differentiating between ischemic and normal hearts during stress echocardiography.
Main Methods:
- Development of a new parameter based on variations of endocardial borders during the cardiac cycle.
- Calculation of the parameter using standard stress echocardiography frames at various heart rates (HRs).
Main Results:
- The novel parameter demonstrated a significant difference between ischemic and normal hearts.
- LV function, as measured by the new parameter, showed distinct responses at different HRs.
Conclusions:
- Ischemic hearts exhibit impaired functional capacity, failing to meet increased activity demands at peak stress.
- The new parameter effectively quantifies LV function and aids in identifying cardiac ischemia during stress echocardiography.
Abstract:
Coronary artery occlusion has a direct effect on cardiac activity and is a well-known reason for ventricular motion disorder, specifically left ventricle (LV) wall motion dysfunction. In stress echocardiography, wall motion abnormality is exaggerated when stress is applied to the heart, and therefore, it is easier to diagnose abnormality in ventricular motion. In this study, we have presented a new parameter that measures LV function. We have shown that LV function can be measured using a variation of endocard borders during a cardiac cycle in standard stress echocardiography frames. This parameter shows a meaningful difference between ischemic and normal hearts and is calculated at different heart rates (HRs). In conclusion, ischemic hearts cannot keep up with the required increase in activity when reaching peak levels of stress.
More Related Videos
09:05Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
08:19Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs
Published on: July 12, 2022
