Related Experiment Video
Updated: Mar 2, 2026

Organ Ischemia-Reperfusion Injury by Simulating Hemodynamic Changes in Rat Liver Transplant Model
Published on: March 6, 2021
Anaesthesia for liver transplantation
Sonali V Thakrar1, Clare N Melikian2
1Clinical Research Fellow in Liver Transplantation and St6 in Anaesthesia, Department of Anaesthetics, Royal Free Perioperative Research Group Royal Free London NHS Foundation Trust, London.
Abstract:
Liver transplantation is a complex procedure that requires a truly multidisciplinary team approach with anaesthetic involvement from the outset in order to ensure excellent outcomes. Before a patient is placed on the waiting list for a liver transplant, a thorough evaluation is undertaken and his/her suitability for transplantation discussed in a patient selection committee meeting. The perioperative management of patients requiring transplantation can be challenging because of the systemic implications of liver disease, approaches to surgical technique and the quality of the grafts used; an increase in the use of marginal donor organs to meet the organ demand poses its own unique difficulties.
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