Related Experiment Video

Updated: Jul 27, 2026

Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion
07:43

Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion

Published on: February 22, 2013

15.5K

Caustic ingestion in children in south of Iran. Retrospective study from Shiraz - Iran

Naser Honar1, Mahmood Haghighat1, Samaneh Mahmoodi1

  • 1Gastroenterohepatology Research Center, Nemazee Teaching Hospital,, Shiraz University of Medical Sciences. Shiraz, Iran.

Revista De Gastroenterologia Del Peru : Organo Oficial De La Sociedad De Gastroenterologia Del Peru
|May 11, 2017
PubMed

Insights

Caustic ingestion in children often causes dysphagia and oral lesions. A significant 20% of pediatric cases developed esophageal stricture, highlighting the need for prompt medical attention.

Area of Science:

  • Pediatric Gastroenterology
  • Toxicology
  • Emergency Medicine

Background:

  • Caustic ingestion poses a significant health risk globally, potentially causing severe esophageal damage in children.
  • Clinical outcomes range from asymptomatic cases to life-threatening complications like perforation and stricture formation.

Purpose of the Study:

  • To evaluate the clinical and endoscopic features and complications of caustic ingestion in pediatric patients in southern Iran.
  • To address the lack of comprehensive regional data on this critical issue.

Main Methods:

  • A retrospective analysis of 75 children admitted with caustic ingestion between 2006 and 2011.
  • Recording of presenting signs and symptoms for each case.

Main Results:

  • The most frequent symptoms observed were dysphagia, oral lesions, vomiting, and drooling.
  • Esophageal injuries occurred with both acid and alkali ingestion, while gastric injuries were more prevalent in acid ingestion.
  • Esophageal stricture developed in 20% of the studied pediatric cases during the follow-up period.

Conclusions:

  • Dysphagia, oral lesions, vomiting, and drooling are the primary clinical indicators of caustic ingestion in children.
  • A notable 20% incidence of esophageal stricture was observed within 3 months of follow-up, underscoring the long-term risks.

More Related Videos

Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils15:04

Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils

Published on: September 28, 2019

6.4K
Rapid and Cost-Effective RNA Extraction of Rat Pancreatic Tissue10:12

Rapid and Cost-Effective RNA Extraction of Rat Pancreatic Tissue

Published on: September 19, 2020

9.9K

Related Concept Videos

Prevention of Further Absorption of Poison01:14

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Pharmaceutical Poisoning: Treatment Strategies01:26

Pharmaceutical Poisoning: Treatment Strategies

Treatment strategies for poisoning are a critical aspect of emergency medicine, focusing on preventing the absorption of toxins and enhancing their elimination. When a poisoning incident occurs, the first response is to halt exposure and decontaminate the patient, particularly through gastrointestinal (GI) methods if the poison was ingested.Gastrointestinal Decontamination Techniques:Activated charcoal is the cornerstone of GI decontamination. It works through adsorption, binding the toxin to...