[An analysis of transmission in the interneuronal synapses using a convolution of binomial distributions]

The convolution of two binomial distributions has been used for the analysis of the discrete distributions of the elementary EPSPs amplitude in the sensorimotor, proprio- and reticulo-motoneuronal synapses of the frog. It is shown that the quantity of the working transmitter release sites is higher than that estimated by the binomial distribution. The probability of the release sites response to the single action potential was unequal. In most sites they did not exceed 0.1-0.3 and were supported on the constant level. The effect on the transmitter release mechanism induced blocking of the release sites. The disturbance of preparation to the transmitter release sharply decreased the probability of the release sites response.