[Effect of NF-κB on the pathogenic course of non-alcoholic fatty liver disease]

With the economic growth and better standards of living, the prevalence of non-alcoholic fatty liver disease (NAFLD) is expected to increase dramatically worldwide. NAFLD is a common chronic inflammation disease. NF-κB is a transcription factor that plays crucial roles in inflammation, immunity, cell proliferation and apoptosis. It can facilitate the occurrence and development of NAFLD, and the underlying mechanisms are related to insulin resistance, oxidative stress, alteration of intestinal flora, activation of renin angiotensin system, etc.