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Updated: Mar 2, 2026

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
Propionimicrobium lymphophilum and Actinotignum schaalii bacteraemia: a case report
M Ikeda1,2, T Kobayashi1, T Suzuki1
1Department of Infectious Disease, The University of Tokyo Hospital, Tokyo, Japan.
Abstract:
Propionimicrobium lymphophilum is an anaerobic Gram-positive bacillus that exists in human skin and urinary tract. The pathogenicity is, however, not well known. Only two cases of urinary tract infection have been described recently. In the case presented here, the bacterium was isolated, concomitant with Actinotignum schaalii, from blood culture of a patient with fever and difficulty of urination. The bacteria were identified by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA sequencing. The case was successfully treated with ampicillin/sulbactam.
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