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Updated: Mar 2, 2026

In Vesiculo Synthesis of Peptide Membrane Precursors for Autonomous Vesicle Growth
Published on: June 28, 2019
Selective vesicle aggregation achieved via the self-assembly of terpyridine-based building blocks
Guiping Wang1, Yuanyuan Peng, Lingyun Lou
1College of Chemistry and Chemical Engineering, Southwest Petroleum University, No. 8 Xindu Avenue, Xindu District, Chengdu City, Sichuan Province 610500, People's Republic of China. guangyan.du@gmail.com.
Abstract:
Herein, we report the self-assembly of a mono terpyridine-based building block modified with long alkyl chains, which gives rise to vesicular aggregates in aqueous media. The vesicles are responsive to transition metal ions, and form different kinds of aggregates after metal-ligand coordination. In particular, Ni(ii) shows a unique influence on morphological transitions, whereby vesicles aggregate and fuse upon the addition of Ni(ii) ions. Spectroscopic and morphological studies are highlighted in this work. Furthermore, the formed vesicles could behave as a matrix for encapsulating fluorescent dyes with similar molecular structure via co-assembly, enabling more accurate observation of vesicle aggregation via confocal laser scanning techniques.
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