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Polarization gating based on Mueller matrices.

Angel Lizana1, Albert Van Eeckhout1, Kamil Adamczyk1

  • 1Universitat Autònoma de Barcelona, Grup d'Òptica, Physics Department, Bellaterra, Spain.

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Summary
This summary is machine-generated.

This study generalizes polarization gating (PG) imaging by using Mueller matrix (MM) measurements. Controlling polarization helicity and employing MM decomposition enhances PG-based metrology for tissue imaging.

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Area of Science:

  • Optics and Photonics
  • Biomedical Imaging
  • Mathematical Physics

Background:

  • Polarization gating (PG) techniques are crucial for advanced imaging.
  • Existing PG methods require specific configurations.
  • Mueller matrix (MM) formalism offers a comprehensive description of polarization properties.

Purpose of the Study:

  • To generalize polarization gating (PG) techniques using mathematical formulas.
  • To demonstrate the utility of Mueller matrix (MM) measurements for evaluating various PG configurations.
  • To explore the impact of polarization helicity on PG-based metrology and image contrast.

Main Methods:

  • Development of mathematical formulas generalizing PG techniques.
  • Utilizing measured Mueller matrices (MM) to derive analytical expressions for PG configurations.
  • Investigating the role of polarization helicity in PG metrology.
  • Applying MM decomposition methods for data analysis.

Main Results:

  • Generalization of numerous PG configurations through analytical expressions derived from MM coefficients.
  • Demonstration of polarization helicity's significant impact on sample image contrast.
  • Successful application of the developed method to artificial phantoms and ex-vivo tissues.

Conclusions:

  • The proposed method simplifies the evaluation of PG techniques using MM measurements.
  • Controlling polarization helicity is key for optimizing PG-based imaging contrast.
  • Combining PG with MM analysis provides a powerful tool for polarimetric metrology in biological samples.