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Very late presentation of a disorder of sex development
J M Martins1,2, M Fraga2,3, J Miguens4
1Endocrine Department, Hospital Santa Maria, Lisbon, Portugal.
Abstract:
Disorders of sex development generally present in the neonatal period with ambiguity of external genitalia. We report a very old male patient presenting at 75 years because of panhypopituitarism and a large nonsecreting pituitary macroadenoma secondary to long-standing primary hypogonadism due to 46,XX sex reversal disorder now first diagnosed. Sex development disorders may go unrecognised for the entire life span, despite infertility and long-standing primary gonadic failure may lead to uncommon complications.
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