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Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
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ADE-ing and Abetting Zika

Jinsheng Wen1, Sujan Shresta2

  • 1Division of Inflammation Biology, La Jolla Institute for Allergy & Immunology, La Jolla, CA 92037, USA; Institute of Arboviruses, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.

Cell Host & Microbe
|May 12, 2017
PubMed

Although dengue virus (DENV) antibodies can neutralize or enhance Zika virus (ZIKV) infection in vitro, their contribution to ZIKV infection in vivo remains unclear. In a recent issue of Science, Bardina et al. (2017) explore the protective versus pathogenic roles of DENV-immune antibodies in ZIKV infection using a mouse model.

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