Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

π Electron Effects on Chemical Shift: Overview01:27

π Electron Effects on Chemical Shift: Overview

1.8K
An applied magnetic field causes loosely bound π-electrons in organic molecules to circulate, producing a local or induced diamagnetic field over a large spatial volume. As the molecules tumble in solution, the field generated by π-electrons in spherical substituents results in a zero net field. However, the net field generated by π-electrons in non-spherical substituents is not zero. The effect of this induced field depends on the orientation of the molecule with respect to B0,...
1.8K
Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

1.3K
The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
1.3K
Atomic Nuclei: Nuclear Relaxation Processes01:23

Atomic Nuclei: Nuclear Relaxation Processes

1.3K
In the absence of an external magnetic field, nuclear spin states are degenerate and randomly oriented. When a magnetic field is applied, the spins begin to precess and orient themselves along (lower energy) or against (higher energy) the direction of the field. At equilibrium, a slight excess population of spins exists in the lower energy state. Because the direction of the magnetic field is fixed as the z-axis,  the precessing magnetic moments are randomly oriented around the z-axis.
1.3K
Diamagnetic Shielding of Nuclei: Local Diamagnetic Current01:14

Diamagnetic Shielding of Nuclei: Local Diamagnetic Current

1.5K
An applied magnetic field causes the electrons present in the molecule to circulate, setting up a local diamagnetic current within the molecule. The local diamagnetic current arising from circulating sigma-bonding electrons induces a magnetic field, Blocal that opposes the applied magnetic field, B0. The effective magnetic field experienced by these nuclei is given by the difference between the applied and local magnetic fields in a phenomenon called local diamagnetic shielding. Essentially,...
1.5K
NMR Spectroscopy: Spin–Spin Coupling01:08

NMR Spectroscopy: Spin–Spin Coupling

3.4K
The spin state of an NMR-active nucleus can have a slight effect on its immediate electronic environment. This effect propagates through the intervening bonds and affects the electronic environments of NMR-active nuclei up to three bonds away; occasionally, even farther. This phenomenon is called spin–spin coupling or J-coupling. Coupling interactions are mutual and result in small changes in the absorption frequencies of both nuclei involved. While nuclei of the same element are involved...
3.4K
π Electron Effects on Chemical Shift: Aromatic and Antiaromatic Compounds01:14

π Electron Effects on Chemical Shift: Aromatic and Antiaromatic Compounds

2.0K
In aromatic compounds, such as benzene, the circulation of (4n + 2) π-electrons sets up a diamagnetic or diatropic ring current around the perimeter of the molecule. This current induces a magnetic field that opposes the external field inside the ring and reinforces it on the outside. The protons in benzene are deshielded and exhibit high chemical shifts in the range 6.5–8.5 ppm. The shielding effect at the center of the ring is evident in complex aromatic molecules, such as...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Importance of strength training for sustaining performance and health in military personnel.

BMJ military health·2024
Same author

Aerobic fitness predicted by demographics, anthropometrics, health behaviour, physical activity and muscle fitness in male and female recruits entering military service.

BMJ military health·2022
Same author

Changes in physical fitness and anthropometrics differ between female and male recruits during the Finnish military service.

BMJ military health·2020
Same author

Orienting spins in dually doped monolayer MoS<sub>2</sub>: from one-sided to double-sided doping.

Chemical communications (Cambridge, England)·2017
Same author

Benzene at 1GHz. Magnetic field-induced fine structure.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2015
Same author

Field-induced alignment of the nematic director: studies of nuclear magnetic resonance spectral oscillations in the limit of fast director rotation.

The Journal of chemical physics·2011

Related Experiment Video

Updated: Mar 2, 2026

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy
08:55

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy

Published on: October 9, 2020

6.1K

Magnetic field-induced effects on NMR properties.

J Jokisaari1, A M Kantola1, J Vaara1

  • 1University of Oulu, NMR Research Unit, P.O. Box 3000, FI-90014, Finland.

Journal of Magnetic Resonance (San Diego, Calif. : 1997)
|May 12, 2017
PubMed
Summary

Nuclear Magnetic Resonance (NMR) observables show magnetic field dependence. This study quanties the indirect magnetic field effect on spin-spin couplings and quadrupole coupling in deuterated benzene, revealing significant contributions at common NMR field strengths.

Keywords:
1,3,5-D3-benzeneDiamagnetic anisotropyIsotope effectIsotropic liquidMolecular orientation

More Related Videos

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

20.2K
Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

10.0K

Related Experiment Videos

Last Updated: Mar 2, 2026

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy
08:55

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy

Published on: October 9, 2020

6.1K
Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
09:30

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease

Published on: December 18, 2016

20.2K
Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

10.0K

Area of Science:

  • Physical Chemistry
  • Nuclear Magnetic Resonance Spectroscopy
  • Quantum Chemistry

Background:

  • Nuclear Magnetic Resonance (NMR) observables, including spin-spin coupling (J), nuclear shielding (σ), and quadrupole coupling (q), are fundamentally dependent on the applied magnetic field.
  • This magnetic field dependence can manifest directly, through deformation of the molecular electronic cloud, or indirectly, via anisotropic molecular orientation distributions influenced by magnetic susceptibility.

Purpose of the Study:

  • To investigate and quantify the indirect magnetic field dependence of one-bond Hydrogen-Carbon (¹H-¹³C) and Deuterium-Carbon (²H-¹³C) spin-spin couplings (J couplings) and Deuterium (²H) quadrupole coupling.
  • To determine the susceptibility anisotropy, ²H quadrupole coupling constant, asymmetry parameter, and extrapolated one-bond CH and CD coupling constants at vanishing field strength using 1,3,5-D₃-benzene as a model system.

Main Methods:

  • Experimental NMR measurements were conducted on 1,3,5-D₃-benzene at four distinct magnetic fields: 4.7, 9.4, 14.1, and 18.8 Tesla.
  • A joint fitting procedure was employed to analyze data acquired at different field strengths, enabling the extraction of key physical parameters.
  • The study focused on characterizing the indirect magnetic field effect, distinguishing it from direct effects.

Main Results:

  • The indirect magnetic field effect was found to be significant even at magnetic fields commonly utilized in modern NMR spectrometers.
  • Experimental values for susceptibility anisotropy, ²H quadrupole coupling constant, asymmetry parameter, and one-bond CH and CD coupling constants extrapolated to zero field were successfully determined.
  • The determined field-induced contributions were observed to surpass typical error margins for coupling constants, and a primary isotope effect on the one-bond CH coupling constant was indicated.

Conclusions:

  • The indirect magnetic field effect plays a substantial role in NMR measurements, influencing key spectroscopic parameters.
  • Increasing magnetic field strengths in NMR spectroscopy will lead to more pronounced indirect, and potentially direct, magnetic field effects.
  • Accurate determination of NMR parameters requires careful consideration and correction for magnetic field-dependent phenomena, especially at high fields.