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Related Experiment Videos

Ramires Alsamir Tibana1, Octávio Luiz Franco1,2, Rinaldo Wellerson Pereira1,2

  • 1Universidade Católica de Brasília. Programa de Pós-Graduação Stricto Sensu em Educação Física. Brasília, DF, Brasil.

Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [And] German Diabetes Association
|May 12, 2017
PubMed
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Maternal exercise before and after conception can prevent metabolic syndrome risk factors in offspring. Paternal exercise effects are currently inconclusive, warranting further research into exercise

Area of Science:

  • Reproductive biology and exercise physiology
  • Metabolic health and disease prevention
  • Epigenetics and developmental programming

Background:

  • Metabolic syndrome (MetS) involves multiple cardiovascular risk factors.
  • Exercise during pregnancy shows benefits, but periconceptional exercise effects on offspring are less understood.
  • Epigenetic modifications may mediate exercise-induced metabolic programming.

Purpose of the Study:

  • To review the effects of pre- and post-periconceptional exercise on offspring's metabolic syndrome risk factors.
  • To analyze findings from experimental models using both paternal and maternal exercise.
  • To identify research gaps regarding exercise type, timing, and dosage.

Main Methods:

  • Systematic review of experimental studies on exercise before, during, and after periconception.

Related Experiment Videos

  • Focus on aerobic exercise interventions and their impact on offspring's MetS risk factors.
  • Exclusion of studies solely focused on resistance exercise.

    • Main Results:

    • Aerobic exercise before and after periconception demonstrated preventive effects on offspring's MetS risk factors.
    • Maternal exercise showed more consistent positive outcomes compared to paternal exercise.
    • Paternal exercise studies yielded inconclusive results regarding MetS risk factors in offspring.

    Conclusions:

    • Periconceptional maternal exercise is a promising strategy for preventing MetS risk factors in offspring.
    • Further research is needed to explore exercise dose-response relationships and paternal exercise effects.
    • Epigenetic mechanisms like DNA methylation and non-coding RNAs may underlie exercise-induced metabolic programming.