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Complex regional pain syndrome type 1 predictors - Epidemiological perspective from a national database analysis
Ahmad Elsharydah1, Nathaniel H Loo1, Abu Minhajuddin1
1University of Texas Southwestern Medical Center, Department of Anesthesiology and Pain Management, Dallas, TX, United States.
Journal of Clinical Anesthesia
|May 13, 2017
Summary
Complex regional pain syndrome type 1 (CRPS1) risk factors include female gender, Caucasian race, and higher income. Conditions like diabetes and obesity were associated with lower CRPS1 rates in this inpatient study.
Area of Science:
- Pain Medicine
- Epidemiology
- Health Services Research
Background:
- Complex regional pain syndrome type 1 (CRPS1) is a debilitating condition with an unknown cause, often following limb injury.
- Understanding CRPS1 risk factors is crucial for early identification and management.
Purpose of the Study:
- To investigate the risk factors and predictors of CRPS1 using a large national inpatient database.
- To identify patient demographics and comorbidities associated with CRPS1 diagnosis.
Main Methods:
- Retrospective analysis of the Nationwide Inpatient Sample (NIS) database (2007-2011).
- Inclusion of adult inpatients with a diagnosis of CRPS1.
- Statistical analyses included chi-square and logistic regression, adjusted for demographics and comorbidities.
Main Results:
- Identified 22,533 CRPS1 cases from over 33 million inpatient records.
- CRPS1 prevalence peaked in individuals aged 45-55.
- Associated factors for higher CRPS1 rates: female gender, Caucasian race, higher income, headache, depression, drug abuse, and private insurance.
- Factors associated with lower CRPS1 rates: diabetes, obesity, hypothyroidism, and anemia.
Conclusions:
- This study provides valuable insights into the risk profile of CRPS1 in an inpatient setting.
- Findings can aid physicians in the early recognition and diagnosis of at-risk patients.
- Further research into CRPS1 etiology and prevention is warranted.
