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Published on: October 27, 2014
The current evidence of statin use affecting glioblastoma prognosis
Victor M Lu1, Kerrie L McDonald1
1Cure Brain Cancer Neuro-oncology Laboratory, Prince of Wales Clinical School, Lowy Cancer Research Centre, University of New South Wales, Sydney, Australia.
Abstract:
Cholesterol-lowering statins have been postulated to improve cancer outcomes by many unconfirmed mechanisms. The prognosis of glioblastoma (GBM) remains dismal, and there is a paucity of evidence regarding the potential for preoperative statins to exert a benefit upon prognosis. In light of a recent report, the current evidence in the literature regarding statin use affecting GBM prognosis is discussed.

