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Published on: July 20, 2022
The Concept of "Burden" in Atrial Fibrillation
Gregg F Rosner1, James A Reiffel1, Kathleen Hickey1
1Department of Medicine, Division of Cardiology, Columbia University Medical Center.
Insights
The term "burden" in atrial fibrillation (AF) has multiple meanings, including electrophysiological, disease, clinical, and economic aspects. Clarifying the specific context of AF burden is essential for accurate scientific communication.
Area of Science:
- Cardiology
- Medical Informatics
Background:
- The term "burden" is increasingly used in atrial fibrillation (AF) research.
- Its common usage often refers to the electrophysiological measure of time spent in AF.
- However, AF burden encompasses broader concepts like disease, clinical, and economic impact.
Purpose of the Study:
- To delineate the various interpretations of "burden" in the context of atrial fibrillation.
- To highlight the importance of precise terminology in AF research and clinical practice.
Main Methods:
- Literature review and conceptual analysis of the term "burden" in AF publications.
- Categorization of AF burden into distinct contexts: electrophysiological, disease, clinical, and economic.
Main Results:
- Identification of multiple meanings for "burden" in AF, beyond the electrophysiological definition.
- Recognition that different AF burden metrics can evolve independently during disease progression and treatment.
Conclusions:
- Authors and readers must clearly define the specific meaning of "burden" when discussing atrial fibrillation.
- Standardized terminology will improve clarity and consistency in AF research and patient care.
Abstract:
Over the last decade or so the term "burden" has become frequently encountered in manuscripts discussing atrial fibrillation (AF). AF "burden" is perhaps most commonly encountered in the electrophysiological context - the amount of time the patient is in AF out of the total monitored time (i.e., the percent of time one is in AF). However, "burden" in AF may also be used in other contexts, which we characterize below as "disease burden", "clinical burden," "economic burden." Over the course of the disease progression and its therapy, such "burdens" may change, and may do so in parallel with each other or in opposite directions. This manuscript explores these various concepts of AF "burden" so as to emphasize to authors and readers that when using the term, its meaning must be made clear.
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