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Heart failure with preserved ejection fraction: a nephrologist-directed primer
Baris Afsar1, Patrick Rossignol2,3,4,5, Loek van Heerebeek6
1Department of Medicine, Division of Nephrology, Suleyman Demirel University School of Medicine, Faculty of Medicine, 32260, Isparta, Turkey. afsarbrs@yahoo.com.
Heart failure and kidney failure often coexist. This review focuses on heart failure with preserved ejection fraction (HFpEF), its diagnosis, and treatment, emphasizing kidney-related aspects for better patient care.
Area of Science:
- Cardiology
- Nephrology
- Internal Medicine
Background:
- Growing interaction between heart failure (HF) and renal failure patients.
- Heart failure with preserved ejection fraction (HFpEF) is prevalent, difficult to diagnose, and rising.
- Current treatments for HFpEF offer limited improvements in exercise tolerance and morbidity.
Purpose of the Study:
- To review kidney-related concepts crucial for diagnosing and treating HFpEF.
- To explore the clinical aspects of HFpEF and its impact on renal function.
- To provide a comprehensive overview of HFpEF management in relation to kidney health.
Main Methods:
- Literature review focusing on the intersection of HFpEF and renal failure.
- Analysis of diagnostic criteria and treatment strategies for HFpEF.
- Examination of clinical data and research findings on HFpEF management.
Main Results:
- HFpEF diagnosis and management are complex due to comorbidities.
- Kidney function significantly influences HFpEF outcomes.
- Limited evidence-based treatments exist for HFpEF, highlighting the need for further research.
Conclusions:
- Understanding kidney-related factors is essential for effective HFpEF management.
- Integrated care approaches are needed for patients with coexisting HFpEF and renal issues.
- Further research is required to develop targeted therapies for HFpEF.
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