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Published on: August 9, 2024
[Choosing wisely recommendations in cardiology]
K Werdan1,2, S Baldus3,4, N Frey3,5
1Deutsche Gesellschaft für Kardiologie - Herz- und Kreislaufforschung, Grafenberger Allee 100, 40237, Düsseldorf, Deutschland. karl.werdan@medizin.uni-halle.de.
Insights
German Cardiac Society guidelines suggest anticoagulation for moderate stroke risk atrial fibrillation patients and goal-directed LDL cholesterol lowering for coronary heart disease. These recommendations aim to optimize patient outcomes and treatment strategies.
Area of Science:
- Cardiology
- Preventive Medicine
Background:
- Controversial Choosing Wisely recommendations from the German Cardiac Society are discussed.
- These include anticoagulation for moderate stroke risk atrial fibrillation and goal-directed LDL cholesterol lowering.
Purpose of the Study:
- To analyze the German Cardiac Society's recommendations on anticoagulation for atrial fibrillation and LDL cholesterol management.
- To discuss the rationale behind prioritizing goal-oriented statin therapy over fixed-dose strategies.
Main Methods:
- Review of German Cardiac Society guidelines.
- Analysis of recommendations for atrial fibrillation and coronary heart disease patient management.
Main Results:
- Anticoagulation therapy benefits patients with atrial fibrillation and moderate stroke risk (CHA2DS2-VASc Score 1 in men, 2 in women), including the elderly.
- For coronary heart disease, a target LDL cholesterol below 70 mg/dl (1.8 mmol/l) or at least a 50% reduction from baseline is recommended.
Conclusions:
- The German Cardiac Society emphasizes goal-oriented statin therapy for LDL cholesterol reduction.
- These guidelines aim to refine treatment strategies for atrial fibrillation and coronary heart disease.
Abstract:
This article describes controversially discussed Choosing wisely recommendations presented by the German Cardiac Society: anticoagulation therapy in patients with atrial fibrillation and "only" moderate stroke risk, on the one hand, and goal-directed low-density lipoprotein (LDL) cholesterol-lowering, on the other. Presuming an adequate regime, patients with atrial fibrillation and only moderate risk of stroke (CHA2DS2-VASc Score of 1 in men and of 2 in women) also benefit from anticoagulation therapy, even in elderly patients. In patients with coronary heart disease, the German Cardiac Society recommends reducing LDL-cholesterol serum levels with a statin to values lower than 70 mg/dl (1.8 mmol/l) or at least reducing the basal level by 50%. With this recommendation, the German Cardiac Society unequivocally prioritizes the "goal-oriented statin therapy" above the "statin strategy of fixed dose". The reasons for this preference are discussed.
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