Related Experiment Video
Updated: Mar 2, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
Published on: December 20, 2024
Assessment of validity and reliability of Drug Hypersensitivity Quality of Life Questionnaire: The Dutch experience
M Moayeri1, H Van Os-Medendorp1, I Baiardini2
1Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands.
Summary:
Drug Hypersensitivity Quality of Life Questionnaire (DrHy-Q) is the first questionnaire that captures health related quality of life impact in patients with drug hypersensitivity. The aim of this study was to translate and validate the original Italian 15-item DrHy-Q for use among Dutch-speaking residents. We also compared the DrHy-Q scores obtained across countries. In a prospective cohort study, the Dutch DrHy-Q was completed by 124 patients (65.3% female, age 56.8 ± 14.0) with a confirmed drug hypersensitivity. Median DrHy-Q score was 12 [0-88]. Validity and reliability of the DrHy-Q was confirmed through, 1, confirmatory factor analysis; 2, concurrent validity with a generic health related quality of life questionnaire (RAND-36); 3, internal consistency; and 4, test-retest reliability. A country specific difference in scores was observed.
Related Concept Videos
Drug toxicity: Idiosyncratic Reactions
Bioavailability Study Design: Healthy Subjects Versus Patients
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Drug Toxicity: Allergic Reactions
Drug Dissolution: Requirements and Profile Comparison
Measurement of Bioavailability: Pharmacodynamic Methods

