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Updated: Mar 2, 2026

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
Published on: April 28, 2022
Surface-Enhanced Raman Spectroscopy: A Facile and Rapid Method for the Chemical Component Study of Individual
Yu Fu1, Christian Kuppe2, Ventsislav K Valev2
1Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention, Department of Environmental Science & Engineering, Fudan University , Shanghai 200433, People's Republic of China.
Abstract:
A simple and rapid method for detecting chemical components of individual aerosol particles on Klarite substrate with surface-enhanced Raman spectroscopy (SERS) is described. For both single simulated aerosol particles and ambient atmospheric particles, this new analytical method promotes the enhancement factor of the Raman signal. The spectra of ammonium sulfate and naphthalene particles at the microscopic level are enhanced by a factor of 6 and therefore greatly improve the detection of the chemical composition of an individual aerosol particle. When aerosol particles are found over a microscopic domain, a set of Raman spectra with chemical information can be obtained via SERS mapping. The maps illustrate the distribution of organic or inorganic species on the SERS substrate. This constitutes a facile and rapid method to study aerosol particles. This new method allows the analysis of chemical composition in single aerosol particles, demonstrating the power of SERS to probe the ambient atmospheric particles and to study the formation of aerosol particles.
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