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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Related Experiment Video

Updated: Mar 2, 2026

Author Spotlight: Optimizing Micro-Drive Systems for Precise Electrode Positioning in Marmoset

Author Spotlight: Optimizing Micro-Drive Systems for Precise Electrode Positioning in Marmoset

Published on: August 4, 2023

A geometrically adjustable receive array for imaging marmoset cohorts.

Kyle M Gilbert¹, Joseph S Gati¹, L Martyn Klassen¹

¹Centre for Functional and Metabolic Mapping, The University of Western Ontario, 1151 Richmond St. N, London, Ontario, Canada N6A 5B7.

|May 14, 2017

Summary

Researchers developed an adjustable 8-channel radiofrequency coil for high-resolution magnetic resonance imaging (MRI) in common marmosets. This coil improves signal-to-noise ratio (SNR) and accommodates varying head sizes, crucial for neuroscience research.

Keywords:

Functional imaging MRI Marmoset Parallel imaging RF coil Receive coil

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Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

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Last Updated: Mar 2, 2026

Author Spotlight: Optimizing Micro-Drive Systems for Precise Electrode Positioning in Marmoset

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Published on: August 4, 2023

Stereotaxic Surgery for Implantation of Microelectrode Arrays in the Common Marmoset Callithrix jacchus

Stereotaxic Surgery for Implantation of Microelectrode Arrays in the Common Marmoset Callithrix jacchus

Published on: September 29, 2019

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities

Published on: October 27, 2023

Area of Science:

Neuroscience
Biomedical Engineering
Magnetic Resonance Imaging

Background:

The common marmoset (Callithrix jacchus) is a key model organism in translational neuroscience.
High-resolution anatomical and functional MRI are vital tools for marmoset research.
Existing radiofrequency coils often lack optimization for marmoset head size variability, hindering high signal-to-noise ratio (SNR) acquisitions and accelerated imaging.

Purpose of the Study:

To design and evaluate an adjustable 8-channel phased-array receive coil for small-animal MRI.
To improve SNR and accommodate size heterogeneity in common marmoset populations.
To enable efficient and high-quality anatomical and echo-planar imaging in marmoset neuroscience studies.

Main Methods:

An 8-channel phased-array receive coil was engineered with adjustable width for common marmoset heads.
The coil was tested on two marmosets of differing head sizes using a 9.4-T small-animal MRI scanner.
Performance was assessed by comparing SNR and geometry factors against a standard 15-channel coil.

Main Results:

The adjustable coil maintained consistent SNR across the brain periphery for different head sizes.
It achieved significantly higher SNR compared to a standard 15-channel coil: 57% in superior frontal/parietal cortices and 29% in the brain center.
The adjustable coil demonstrated a mean geometry factor below 1.2 for 2-fold acceleration, indicating suitability for accelerated acquisitions.

Conclusions:

The adjustable 8-channel coil offers a practical solution for high-SNR MRI in common marmosets, addressing head size variability.
This coil design enhances imaging efficiency and data quality for anatomical and echo-planar imaging in marmoset neuroscience.
The developed coil facilitates the study of larger marmoset cohorts, advancing translational neuroscience research.