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A plague of actin disassembly

Shoichiro Ono1

  • 1From the Departments of Pathology and Cell Biology and Winship Cancer Institute, Emory University, Atlanta, Georgia 30322 sono@emory.edu.

The Journal of Biological Chemistry
|May 14, 2017
PubMed
Summary

Pathogenic Yersinia bacteria use the YopO kinase to block immune cells. YopO activates gelsolin, disrupting actin filaments essential for macrophage function.

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