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Hospitalization for Charcot neuroarthropathy in diabetes: A population study in Italy

Roberto Anichini1, Laura Policardo2, Flavia Lucia Lombardo3

  • 1Diabetes Unit and Diabetes Foot Unit, San Jacopo Hospital, USL Centro-Toscana, Pistoia, Italy.

Diabetes Research and Clinical Practice
|May 14, 2017
PubMed

Insights

Charcot neuroarthropathy (CN) is infrequent in diabetic populations in Italy, with declining incidence in Tuscany. CN patients face higher risks of amputation and infection but similar revascularization needs compared to non-Charcot diabetic foot patients.

Area of Science:

  • Epidemiology
  • Diabetology
  • Vascular Surgery

Background:

  • Charcot neuroarthropathy (CN) is a severe complication of diabetic neuropathy.
  • Understanding CN's epidemiological trends and its impact on lower limb procedures is crucial for patient management.

Purpose of the Study:

  • To analyze hospitalization and incidence rates of Charcot neuroarthropathy (CN) in Italy and Tuscany.
  • To investigate the association of CN with lower limb amputations and revascularizations in diabetic patients.

Main Methods:

  • Retrospective analysis of hospitalizations for CN (ICD-9-CM codes 7130, 7135, 7138) in diabetic populations.
  • Evaluation of amputation, revascularization, peripheral vascular disease, and infection rates between 2003-2013 (Italy) and 2008-2015 (Tuscany).

Main Results:

  • CN hospitalizations were infrequent, with incidence rates per 100,000 diabetic patients ranging from 11-14 in Italy and declining to 7 in Tuscany.
  • CN patients were younger, had longer hospital stays, and significantly higher rates of amputation and infection compared to non-Charcot diabetic foot patients.
  • Revascularization rates were similar between CN and non-Charcot diabetic foot patients.

Conclusions:

  • Charcot neuroarthropathy affects a small percentage of diabetic patients, with stable incidence in Italy and a recent decline in Tuscany.
  • CN is linked to younger age, prolonged hospitalization, and increased risk of amputations and infections.
  • The need for revascularization in CN patients is comparable to those with non-Charcot diabetic foot.
Abstract

Keywords:
AmputationsCharcot neuroarthropathyDiabetic footHospitalization ratePopulation study

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