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[Possibility of using saliva as a diagnostic test material in cardiovascular diseases]

Małgorzata Klichowska-Palonka1, Katarzyna Załęska-Chromińska1, Teresa Bachanek1

  • 1Katedra i Zakład Stomatologii Zachowawczej z Endodoncją, Uniwersytet Medyczny, Lublin.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|May 15, 2017
PubMed

Insights

Saliva analysis offers a non-invasive, cost-effective method for detecting cardiovascular disease biomarkers. This systematic review highlights saliva

Area of Science:

  • Cardiovascular diagnostics
  • Biomarker discovery
  • Salivary diagnostics

Context:

  • Cardiovascular diseases (CVDs) pose a significant global health burden.
  • Late diagnosis of CVDs leads to severe complications and increased healthcare costs.
  • There is a need for accessible, rapid, and affordable diagnostic tools for CVDs.

Purpose:

  • To systematically review existing literature on salivary biomarkers for cardiovascular diseases.
  • To evaluate the potential of saliva as a diagnostic medium for CVD risk markers.
  • To identify promising classical and novel biomarkers detectable in saliva.

Summary:

  • Saliva collection is non-invasive, painless, and cost-effective compared to blood sampling.
  • Diagnostic tests for cardiovascular conditions, including high-sensitivity C-reactive protein (hs-CRP), cortisol, CK-MB, troponin, and myoglobin, can be performed using saliva.
  • Salivary biomarkers show potential for screening, epidemiological studies, and clinical diagnostics of cardiovascular diseases.

Impact:

  • Saliva-based diagnostics can improve early detection and management of cardiovascular diseases.
  • Non-invasive salivary testing may increase patient compliance and accessibility to screening.
  • This approach could reduce healthcare costs associated with traditional diagnostic methods.
Abstract

Keywords:
CHD-coronary heart diseaseCVD -cardiovascular diseasesatherosclerosisserumstate of oral healthsaliva

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