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Modiolar ossification in paediatric patients with auditory neuropathy

L Wang1, Z Wang1, F Gao1

  • 1Department of Otorhinolaryngology - Head and Neck Surgery,Beijing Friendship Hospital,Capital Medical University,China.

The Journal of Laryngology and Otology
|May 16, 2017
PubMed

Insights

Paediatric patients with auditory neuropathy (AN) show increased modiolar ossification, a finding significant for cochlear implantation success. This CT scan finding aids in evaluating AN patients for auditory implants.

Area of Science:

  • Otolaryngology
  • Neuroradiology
  • Pediatric Audiology

Background:

  • Auditory neuropathy (AN) is a condition affecting hearing in children.
  • Cochlear implantation is a treatment option for severe hearing loss.
  • Ossification of the modiolus may impact cochlear implant outcomes.

Purpose of the Study:

  • To report on increased modiolar ossification in pediatric patients with AN.
  • To compare modiolar ossification between AN patients and those with sensorineural hearing loss (SNHL) undergoing cochlear implantation.

Main Methods:

  • Retrospective case series with a comparison group.
  • Seven pediatric patients with AN undergoing cochlear implantation.
  • Fifteen pediatric patients with SNHL as a comparison group.
  • Pre-operative computed tomography (CT) scans analyzed for modiolar attenuation by a blinded neuroradiologist.

Main Results:

  • Modiolar attenuation values were significantly higher in AN patients (796.2 ± 53.0 HU) compared to SNHL patients (267.1 ± 45.6 HU).
  • The difference in modiolar attenuation was statistically significant (p < 0.05).

Conclusions:

  • Pediatric patients with AN meeting cochlear implantation criteria exhibit significantly increased modiolar attenuation on CT imaging.
  • This finding suggests increased ossification of the modiolus in this patient group.
  • Modiolar ossification may be a relevant factor in the pre-operative assessment of pediatric AN patients for cochlear implantation.
Abstract

Keywords:
Auditory NeuropathyCochleaCochlear Implants

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