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Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

855
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

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Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
868
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Related Experiment Video

Updated: Mar 2, 2026

Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis
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Evaluating Therapeutic Interventions in the SHIP-deficient Mouse Model of Crohn Disease-like Ileitis and Fibrosis

Published on: October 14, 2025

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Pediatric Inflammatory Bowel Disease.

Máire A Conrad1, Joel R Rosh2

  • 1Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.

Pediatric Clinics of North America
|May 16, 2017
PubMed
Summary
This summary is machine-generated.

Pediatric inflammatory bowel disease (IBD) requires endoscopic diagnosis and treatment focused on remission, growth, and quality of life. Key goals include mucosal healing and minimizing medication side effects for children with Crohn disease or ulcerative colitis.

Keywords:
AdolescentsCrohnInflammatory bowel diseasePediatricsUlcerative colitis

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Area of Science:

  • Gastroenterology
  • Pediatric Medicine
  • Immunology

Background:

  • Inflammatory bowel disease (IBD) encompasses Crohn disease, ulcerative colitis, and IBD-unspecified.
  • It is a chronic, immune-mediated condition affecting the gastrointestinal tract.
  • Treatment aims for durable remission in affected individuals.

Purpose of the Study:

  • To outline the diagnostic and therapeutic goals for pediatric inflammatory bowel disease.
  • To emphasize the importance of early and accurate diagnosis in children.
  • To highlight comprehensive management strategies for IBD in pediatric patients.

Main Methods:

  • Diagnosis is confirmed through esophagogastroduodenoscopy and colonoscopy.
  • Assessment involves evaluating a wide spectrum of presenting symptoms in pediatric patients.
  • Treatment strategies are tailored to individual patient needs.

Main Results:

  • Endoscopic procedures are crucial for confirming IBD diagnosis in children.
  • Pediatric IBD presents with diverse symptoms requiring careful evaluation.
  • Treatment success is measured by remission, growth, and quality of life.

Conclusions:

  • Achieving and maintaining remission is the primary treatment goal for pediatric IBD.
  • Mucosal healing, optimal growth, and minimized medication toxicity are critical outcomes.
  • Improving the quality of life for pediatric patients with IBD is paramount.