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Intestinal Transplant in Children

Nidhi Rawal1, Nada Yazigi2

  • 1Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Maryland Medical Center, 22 South Green Street, Baltimore, MD 21201, USA.

Pediatric Clinics of North America
|May 16, 2017
PubMed

Insights

Pediatric intestinal transplantation has improved significantly, with one-year survival rates now between 85% and 90%. Advances in multidisciplinary care are key to better outcomes for children with intestinal failure.

Area of Science:

  • Gastroenterology
  • Pediatric Surgery
  • Transplant Medicine

Background:

  • Intestinal transplantation is a vital treatment for pediatric intestinal failure.
  • Significant progress has been made in the last decade.
  • Multidisciplinary care has been crucial for improving outcomes.

Purpose of the Study:

  • To review recent advancements in pediatric intestinal transplantation.
  • To highlight evolving indications and timing for the procedure.
  • To discuss future directions and opportunities in the field.

Main Methods:

  • Review of current literature and transplant center practices.
  • Analysis of survival data and outcomes.
  • Discussion of emerging diagnostic and treatment modalities.

Main Results:

  • One-year mortality for pediatric intestinal transplantation has decreased from 30% to 10%-15%.
  • Multidisciplinary approaches in transplant centers are associated with improved survival.
  • Indications and timing are shifting due to new technologies.

Conclusions:

  • Pediatric intestinal transplantation has seen remarkable success.
  • Ongoing challenges and opportunities exist for further improvement.
  • Future research should focus on refining techniques and expanding access.

Keywords:
IntestinePediatricShort gut syndromeTransplant

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