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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Kidney Transplant II: Surgical Procedure01:26

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Bone Marrow Sampling and Transplants01:22

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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Tissue Transplantation01:24

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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Small Bowel Transplantation In Mice
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Intestinal Transplant in Children.

Nidhi Rawal1, Nada Yazigi2

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Pediatric intestinal transplantation has improved significantly, with one-year survival rates now between 85% and 90%. Advances in multidisciplinary care are key to better outcomes for children with intestinal failure.

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Area of Science:

  • Gastroenterology
  • Pediatric Surgery
  • Transplant Medicine

Background:

  • Intestinal transplantation is a vital treatment for pediatric intestinal failure.
  • Significant progress has been made in the last decade.
  • Multidisciplinary care has been crucial for improving outcomes.

Purpose of the Study:

  • To review recent advancements in pediatric intestinal transplantation.
  • To highlight evolving indications and timing for the procedure.
  • To discuss future directions and opportunities in the field.

Main Methods:

  • Review of current literature and transplant center practices.
  • Analysis of survival data and outcomes.
  • Discussion of emerging diagnostic and treatment modalities.

Main Results:

  • One-year mortality for pediatric intestinal transplantation has decreased from 30% to 10%-15%.
  • Multidisciplinary approaches in transplant centers are associated with improved survival.
  • Indications and timing are shifting due to new technologies.

Conclusions:

  • Pediatric intestinal transplantation has seen remarkable success.
  • Ongoing challenges and opportunities exist for further improvement.
  • Future research should focus on refining techniques and expanding access.