Squamous Cell Carcinomas on Bilateral Feet Arising in Long-Standing Eczematous Lesions

We present a woman with squamous cell carcinomas on both feet in long-standing eczematous lesions. Histopathological examination of biopsies from the both feet revealed highly atypical cells invading the reticular layer of the dermis in the hyperkeratotic lesion and they were associated with surrounding dermatitis with spongiosis. Although the cause and etiology of eczema in our case is unclear, we speculate that the exceptionally long-lasting dermatitis might have induced double SCCs on bilateral feet with an unusual constitution. To the best of our knowledge, this is a first case of SCC on bilateral feet arising in long-standing eczematous lesions.