A new azine derivative colorimetric and fluorescent dual-channel probe for cyanide detection

A novel azine derivative colorimetric and fluorescent dual-channel probe salicylaldehyde hydrazine-3,5-dibromosalicylaldehyde (1) has been designed, synthesized and characterized. The probe 1 is confirmed to have especial selectivity and good sensitivity on detecting CN^- via UV-vis absorption and fluorescence spectrum in aqueous solution (H₂O/DMSO, 1:4, v/v). This colorimetric and fluorescent dual-channel probe response to CN^- owed to the deprotonation process and established the mechanism by using ¹H NMR spectroscopy. Further researches showed that the detection limit of the probe 1 to CN^- anions is 8.01×10^-9M, significantly lower than the maximum level 1.9×10^-6M in potable water from WHO guidelines.