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Electroencephalography Network Indices as Biomarkers of Upper Limb Impairment in Chronic Stroke
Published on: July 14, 2023
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Large-Scale Phase Synchrony Reflects Clinical Status After Stroke: An EEG Study
Teiji Kawano1, Noriaki Hattori1,2, Yutaka Uno2
11 Neurorehabilitation Research Institute, Morinomiya Hospital, Osaka, Japan.
Neurorehabilitation and Neural Repair
|May 17, 2017
Summary
Electroencephalography phase synchrony indices (PSIs) correlate with daily living abilities but not motor skills in stroke patients. This suggests PSIs may serve as a novel marker for stroke recovery and clinical status.
Area of Science:
- Neuroscience
- Clinical Neurology
- Biomedical Engineering
Background:
- Stroke impacts neural networks, causing remote effects.
- Electroencephalography (EEG) and phase synchrony analysis can detect these neural modifications.
- Few studies have explored EEG phase synchrony in stroke patients.
Purpose of the Study:
- To investigate the clinical relevance of hemispheric phase synchrony in stroke patients.
- To correlate phase synchrony indices with clinical status assessments.
Main Methods:
- Cross-sectional study of 19 post-acute ischemic stroke patients.
- Computed interhemispheric phase synchrony indices (IH-PSIs) in alpha and beta bands.
- Analyzed correlations with FIM, NIHSS, and FMA scores.
Main Results:
- IH-PSIs significantly correlated with FIM and NIHSS scores.
- No significant correlation was found between IH-PSIs and FMA scores.
- Intrahemispheric PSIs showed correlation with FIM scores after outlier removal.
Conclusions:
- Phase synchrony indices correlate with functional independence and stroke severity.
- Phase synchrony does not correlate with pure motor function.
- Large-scale phase synchrony, via IH-PSIs, may be a novel surrogate marker for clinical status post-stroke.
