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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
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Cognitive impairment in patients with severe psoriasis
Luiza Marek-Józefowicz1, Marcin Jaracz2, Waldemar Placek3
1Chair of Dermatology, Sexually Transmitted Diseases and Immunodermatology, Faculty of Medicine in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
Postepy Dermatologii I Alergologii
|May 17, 2017
Summary
Patients with psoriasis show impaired frontal cognitive functions, including memory and executive functions, compared to healthy individuals. This cognitive dysfunction is evident in neuropsychological assessments.
Area of Science:
- Neuroscience
- Dermatology
- Psychology
Background:
- Psoriasis is a chronic inflammatory skin condition.
- Psychological factors significantly influence psoriasis.
- Understanding cognitive impacts is crucial for holistic patient care.
Purpose of the Study:
- To evaluate frontal cognitive functions in patients with psoriasis.
- To assess executive functions and memory in psoriatic individuals.
- To compare cognitive performance between psoriasis patients and healthy controls.
Main Methods:
- 188 subjects participated: 97 with psoriasis and 91 healthy controls.
- Dorsolateral prefrontal cortex functions were assessed using the Trail Making Test and Stroop test.
- Psoriasis severity was quantified using the Psoriasis Area and Severity Index (PASI).
Main Results:
- Psoriasis patients demonstrated lower scores on neuropsychological tests compared to healthy controls.
- Impairments were observed in memory and executive functions.
- A correlation between psoriasis severity and cognitive deficits may exist, warranting further investigation.
Conclusions:
- Cognitive dysfunction affecting frontal functions is apparent in individuals with psoriasis.
- Neuropsychological assessment reveals significant deficits in psoriatic patients.
- These findings highlight the need for integrated care addressing both skin and cognitive health in psoriasis management.
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