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Voiding Urosonography with Second-Generation Ultrasound Contrast Agent for Diagnosis of Vesicoureteric Reflux: First

Dafina Kuzmanovska1, Aleksandar Risteski2, Margarita Kambovska2

  • 1University Children's Hospital, Medical Faculty, Ss Cyril and Methodius University of Skopje, Vodnjanska 17, Skopje, Republic of Macedonia.

Open Access Macedonian Journal of Medical Sciences
|May 17, 2017
PubMed

Insights

Contrast-enhanced voiding ultrasonography (ceVUS) effectively detects vesicoureteric reflux (VUR) in children. This radiation-free method is safe and reliable for diagnosing VUR and evaluating the urinary tract.

Area of Science:

  • Pediatric Urology
  • Diagnostic Imaging

Background:

  • Vesicoureteric reflux (VUR) is a common complication of pediatric urinary tract infections (UTIs), affecting 30-50% of children.
  • Contrast-enhanced voiding ultrasonography (ceVUS) is a radiation-free imaging technique for VUR detection.

Purpose of the Study:

  • To review the literature and present findings from a pilot study on ceVUS for VUR detection in children.
  • To evaluate the efficacy of second-generation ultrasound contrast agents in ceVUS.

Main Methods:

  • Retrospective review of 31 ceVUS examinations in children aged 2 months to 18 years.
  • Utilized second-generation ultrasound contrast agent (SonoVue).

Main Results:

  • ceVUS detected VUR in 64.5% of children (20/31), involving 51.6% of nephroureteral units.
  • VUR grades ranged from II to IV.
  • Identified "spinning top urethra" in two girls, indicating functional bladder issues.

Conclusions:

  • ceVUS with second-generation contrast agents is a safe, effective, and reliable alternative for diagnosing VUR in children.
  • The method is suitable for evaluating the pediatric distal urinary tract without radiation exposure.
Abstract

Keywords:
Contrast-enhanced voiding urosonography (ceVUS)Fluoroscopic voiding uretrocystographyVesicoureteric reflux (VUR)pediatric urinary tract infectionradionuclide cystography

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