Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ribosomal RNA Synthesis02:53

Ribosomal RNA Synthesis

15.0K
Ribosome synthesis is a highly complex and coordinated process involving more than 200 assembly factors. The synthesis and processing of ribosomal components occurs not only in the nucleolus but also in the nucleoplasm and the cytoplasm of eukaryotic cells.
Ribosome biogenesis begins with the synthesis of 5S and 45S pre-rRNAs by distinct RNA polymerases. The primary transcripts are extensively processed and modified before they are bound and folded by ribosomal proteins and assembly factors,...
15.0K
Ribosomal RNA Synthesis02:53

Ribosomal RNA Synthesis

4.6K
4.6K
Types of RNA01:20

Types of RNA

10.1K
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in regulating gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA Performs Diverse...
10.1K
Types of RNA01:23

Types of RNA

73.4K
Overview
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...
73.4K
Prokaryotic Gene Structure and Organization01:28

Prokaryotic Gene Structure and Organization

2.5K
Prokaryotic genomes exhibit a streamlined organization of coding and non-coding regions essential for gene expression and protein synthesis. While coding regions contain the genetic instructions for proteins or functional RNAs, non-coding regions regulate the precise transcription and translation of these genes.Coding Regions: Proteins and RNAsThe primary coding regions, known as structural genes, include sequences transcribed into messenger RNA (mRNA) and ultimately translated into...
2.5K
lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

10.0K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
10.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploration Strategies and Feature Prioritisation in Contour-based Haptic Perception of 2D Shape.

IEEE transactions on haptics·2026
Same author

Measuring and reducing surgical staff stress in a realistic operating room setting using EDA monitoring and smart hearing protection.

Frontiers in digital health·2026
Same author

Evaluating the efficiency and ergonomics of a novel smart surgical lighting system: a passive oddball experiment with EEG measurements to assess workplace strain in clinical settings.

Frontiers in medical technology·2025
Same author

TrustNShare - Data Trust Model Balancing Privacy Risk, Reputation, and Incentives.

Studies in health technology and informatics·2025
Same author

Characteristics of men using non-prescription medicines to treat their lower urinary tract symptoms.

World journal of urology·2025
Same author

Mini-GRID therapy delivers optimised spatially fractionated radiation therapy using a flattening free filter accelerator.

Communications medicine·2025
Same journal

Smooth emotional response: amygdalar neurovascular coupling drives stress encoding.

Cell research·2026
Same journal

Liquid surrogates of spatial tumor ecosystems.

Cell research·2026
Same journal

MitoCatch directs mitochondria delivery and prevents cell degeneration.

Cell research·2026
Same journal

Structural basis of sex pheromone detection in aphids.

Cell research·2026
Same journal

Tagging the Tank: Ubiquitin-mediated clearance of cellular energy reserves.

Cell research·2026
Same journal

One-step generation of semi-cloned zebrafish carrying a defined genetic modification.

Cell research·2026
See all related articles

Related Experiment Video

Updated: Mar 2, 2026

Identification of Circular RNAs using RNA Sequencing
08:25

Identification of Circular RNAs using RNA Sequencing

Published on: November 14, 2019

12.9K

Circular RNAs: Coding or noncoding?

Tim Schneider1, Albrecht Bindereif1

  • 1Institute of Biochemistry, Justus Liebig University of Giessen, D-35392 Giessen, Germany.

Cell Research
|May 17, 2017
PubMed
Summary
This summary is machine-generated.

Circular RNAs (circRNAs) are a newly discovered noncoding RNA class. Recent studies show some endogenous circRNAs can surprisingly code for proteins.

More Related Videos

Use of Alu Element Containing Minigenes to Analyze Circular RNAs
13:10

Use of Alu Element Containing Minigenes to Analyze Circular RNAs

Published on: March 10, 2020

7.8K
In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions
10:27

In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions

Published on: October 21, 2022

2.0K

Related Experiment Videos

Last Updated: Mar 2, 2026

Identification of Circular RNAs using RNA Sequencing
08:25

Identification of Circular RNAs using RNA Sequencing

Published on: November 14, 2019

12.9K
Use of Alu Element Containing Minigenes to Analyze Circular RNAs
13:10

Use of Alu Element Containing Minigenes to Analyze Circular RNAs

Published on: March 10, 2020

7.8K
In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions
10:27

In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions

Published on: October 21, 2022

2.0K

Area of Science:

  • Molecular Biology
  • Genetics
  • RNA Biology

Background:

  • Circular RNAs (circRNAs) represent a novel class of RNA molecules.
  • Their functional roles remain largely uncharacterized.
  • Noncoding RNAs typically do not translate into proteins.

Purpose of the Study:

  • To investigate the potential protein-coding capacity of endogenous circRNAs.
  • To explore novel functions beyond noncoding roles for circRNAs.

Main Methods:

  • Analysis of concurrent publications in Cell Research and Molecular Cell.
  • Identification of specific endogenous circRNAs investigated.

Main Results:

  • Initial evidence suggests certain circRNAs can be translated.
  • This challenges the traditional understanding of noncoding RNA function.

Conclusions:

  • Endogenous circRNAs may possess protein-coding capabilities.
  • This opens new avenues for understanding gene expression and regulation.