Related Experiment Video
Updated: Mar 2, 2026

Human Primary Trophoblast Cell Culture Model to Study the Protective Effects of Melatonin Against Hypoxia/reoxygenation-induced Disruption
Published on: July 30, 2016
[Melatonin in a woman's life: from birth to menopause]
E N Usoltseva1, E V Bruhina1, M V Danilova2
1South Ural State Medical University, Chelyabinsk, 454092, Russian Federation; elena-usoltseva@yandex.ru.
Abstract:
We did a review of the literature data of main Russian publications and databases PubMed/Medline for the last 7 years. In the present article we examine the physiology of secretion of pineal hormone melatonin and its role in the vital processes of the body. The study was focused on the influence of melatonin on the female reproductive system, participation in the aging process and the formation of pathological menopause. The article presents research data on the effectiveness of the drug melatonin in the climacteric syndrome. It is revealed that up to the present time according to the literature data there is no information about the standards of secretion of melatonin for women of different age groups, and the lack of secretion of melatonin can be judged by clinical manifestations, and also when compared with groups of healthy women. Remain unclear issues in the application of drugs melatonin at various complications of pregnancy and gynecological diseases. Long-term use of melatonin is still open in climacteric syndrome.
Related Concept Videos
Menopause
The Pineal Gland
The primary secretion of the pineal gland is the hormone melatonin, derived from serotonin. The concentration of melatonin in the...
Management of Insomnia
Understanding Sleep
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
Major Hormones and Their Functions
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...

