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Atherosclerotic vascular diseases have really the same risk factors? Comparison between large abdominal aortic

Dimitri Tsialtas1, Maria Giulia Bolognesi1, Riccardo Volpi1

  • 1Dipartimento di Medicina Interna e, Scienze Biomediche, Sezione di Cardiologia, Università degli Studi di Parma, Parma, Italy.

Vascular
|May 17, 2017
PubMed

Insights

Patients with abdominal aortic aneurysms differ from those with occlusive arterial disease. Aneurysm patients were predominantly male, with diastolic hypertension and impaired kidney function, while occlusive disease patients were more often smokers with hypertriglyceridemia.

Area of Science:

  • Vascular Surgery
  • Cardiovascular Medicine
  • Epidemiology

Background:

  • Abdominal aortic aneurysm (AAA) and occlusive non-coronary arterial disease (OCAD) are manifestations of systemic atherosclerosis.
  • Understanding distinct risk factor profiles is crucial for targeted prevention and management strategies.

Purpose of the Study:

  • To compare clinical conditions and traditional atherosclerotic risk factors between patients with large abdominal aortic aneurysms and those with severe obstructive arterial diseases.
  • To identify differentiating characteristics that may inform clinical practice.

Main Methods:

  • A clinical examination was conducted on 519 patients with asymptomatic abdominal aortic aneurysms.
  • A comparative analysis included 672 patients with severe obstructive arterial diseases prior to surgical repair.
  • Data collected included demographics, lifestyle factors, and biochemical markers.

Main Results:

  • Abdominal aortic aneurysm patients showed a male predominance (p<0.001), higher alcohol consumption (p<0.05), elevated diastolic blood pressure (p<0.05), increased serum creatinine (p<0.005), and were less frequently diabetic (p<0.001).
  • Patients with occlusive atherosclerotic vasculopathies had higher rates of smoking (p<0.05), elevated systolic blood pressure (p<0.05), were more often hypertensive (p<0.05), and exhibited a prevalence of hypertriglyceridemia (p<0.05).

Conclusions:

  • Abdominal aortic aneurysm is associated with male sex, diastolic hypertension, and impaired renal function, with a lower prevalence of diabetes.
  • Occlusive arteriopathy is linked to smoking, hypertension, and hypertriglyceridemia.

Keywords:
Abdominal aortic aneurysmatherosclerotic risk factorsobstructive arterial diseases

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