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Related Concept Videos

Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
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Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices01:28

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

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Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...
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Inhaled Medications01:23

Inhaled Medications

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Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
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Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

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The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
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Additional Routes of Drug Administration01:18

Additional Routes of Drug Administration

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Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
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Insulin Formulations: Types and Delivery01:27

Insulin Formulations: Types and Delivery

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Insulin preparations are categorized by their duration of action into short-acting and long-acting types. Two strategies are used to modify insulin's absorption and pharmacokinetic profile: slowing the absorption post-subcutaneous injection, or altering human insulin's amino acid sequence or protein structure. These changes retain the insulin's ability to bind to the insulin receptor, but alter its behavior in solution or after injection.
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Related Experiment Video

Updated: Mar 2, 2026

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery
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Update on injectables in the nose.

Leo L Wang1, Oren Friedman

  • 1aPerelman School of Medicine bDepartment of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Current Opinion in Otolaryngology & Head and Neck Surgery
|May 17, 2017
PubMed
Summary
This summary is machine-generated.

Nonsurgical rhinoplasty using injectable fillers like hyaluronic acid is popular. While generally successful, physicians must be aware of potential vascular complications and use proper techniques.

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Area of Science:

  • Plastic Surgery
  • Dermatology
  • Aesthetic Medicine

Background:

  • Nonsurgical rhinoplasty utilizing injectable fillers has seen a significant rise in popularity over the last decade.
  • This minimally invasive procedure offers an alternative to traditional surgical rhinoplasty.

Purpose of the Study:

  • To review the most frequently utilized injectable fillers for nonsurgical rhinoplasty.
  • To discuss their established indications and analyze recent findings on both successful outcomes and adverse events.

Main Methods:

  • Literature review of recent reports on injectable fillers for rhinoplasty.
  • Analysis of filler types, success rates, patient satisfaction, and complication profiles.

Main Results:

  • Hyaluronic acid and calcium hydroxylapatite are the predominant fillers employed.
  • While patient satisfaction is generally high, vascular complications remain a significant concern requiring physician vigilance.

Conclusions:

  • Injectable fillers are a viable option for rhinoplasty on a case-by-case basis.
  • Thorough physician knowledge of filler properties, indications, and precise injection techniques is crucial for mitigating serious complications.